CD11c, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD11c, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD11c, Mouse |
| Clone | REA754 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 4x 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11c Antibody, anti-mouse, Biotin, REAfinity™. Clone REA754 recognizes the mouse CD11c antigen, also known as integrin αX or Itgax. CD11c is present in dendritic cells in lymphoid organs and blood, in Langerhans cells in the epidermis, in dendritic cell progenitors in the bone marrow, and in in vitro-generated bone marrow-derived dendritic cells. In spleen and lymph node, CD11c is found at high levels on conventional CD11c+CD45R-mPDCA-1- dendritic cells, and at moderate levels on CD11c+CD45R+mPDCA-1+ plasmacytoid dendritic cells. CD11c is reported to be weakly expressed on NK cells, B cells, and T cell subsets. About 1-3% of splenocytes, 2% of bone marrow cells, as well as <1% of lymph node cells and thymocytes express CD11c. CD11c is a receptor for fibrinogen. It mediates cell-cell interaction during inflammatory responses and is involved in monocyte adhesion and chemotaxis. | Additional information: Clone REA754 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | p150, integrin αX, ITGAX, CR4 |
| Gene, Accession # | Gene ID: 16411 |
| Catalog # | 130-110-699 |
| Price | $865 |
| Order / More Info | CD11c, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Springer, T. A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (2): 301-314. | Lopez-Rodriguez, C. et al. (1996) AP-1 regulates the basal and developmentally induced transcription of the CD11c leukocyte integrin gene. J Immunol 156 (10): 3780-3787. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies