CD69, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD69, Human |
| Clone | REA824 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µg in 100 µL |
| Concentration | n/a |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD69 Antibody, anti-human, pure, REAfinity™. Clone REA824 recognizes the human CD69 antigen, also known as activation inducer molecule (AIM). CD69 is involved in the early events of lymphocyte, monocyte, and platelet activation. Cross-linking of CD69 induces cytotoxic activity and costimulates cytokine production of activated natural killer (NK) cells and selected T cell clones. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. It is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. | Additional information: Clone REA824 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | AIM, BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, VEA |
| Gene, Accession # | Gene ID: 969 |
| Catalog # | 130-124-326 |
| Price | $200 |
| Order / More Info | CD69, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Hamann, J. et al. (1993) Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain. J Immunol 150 (11): 4920-4927. | Lopez-Cabrera, M. et al. (1993) Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors. J. Exp. Med. 178 (2): 537-547. | Lin, G. X. et al. (2002) Cross-reactivity of CD antibodies in eight animal species. In: Leucocyte typing VII, Oxford University Press.: 519-524. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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