TCRγ/δ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityTCRγ/δ, Mouse
CloneREA633
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
FormatVioBlue conjugate
Size9 µg in 300 µL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionTCRγ/δ Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA633 recognizes the mouse TCRγ/δ antigen. The T cell receptor (TCR) is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules. | Additional information: Clone REA633 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesTCRgd
Gene, Accession #Gene ID: 110066, 110067
Catalog #130-110-404
Price$76
Order / More InfoTCRγ/δ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesSchmolka, N. et al. (2013) Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory γδ T cell subsets. Nat Immunol 14 (10): 1093-1100. | Bonneville, M. et al. (2010) Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10 (7): 467-478. | Wiest, D. L. (2016) Development of γδ T cells, the special-force soldiers of the immune system. Methods Mol. Biol. 1323: 23-32.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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