CD87, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

Search, find, compare suppliers for anti-CD87, Human antibody, protein, ELISA kits.

Edit 
Antigenic SpecificityCD87, Human
CloneVIM5
Host SpeciesMouse
Reactive Specieshuman, nonhuman primate
IsotypeIgG1κ
Formatallophycocyanin (APC) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCD87 Antibody, anti-human, APC. Clone VIM5 recognizes CD87, a 36-38 kDa GPI-anchored cell-surface receptor. CD87, also known uPAR, binds uPA and thus facilitating the catalytic C domain of the uPA to come in close proximity of membrane bound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in-turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. The expression of membrane-bound CD87 is found on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells, and keratinocytes. Multiple known regulatory functions of CD87 include cell migration, leukocyte adhesion, chemotaxis, signal transduction, and tissue remodeling.
Immunogenn/a
Other NamesPLAUR, U-PAR, URKR
Gene, Accession #Gene ID: 5329
Catalog #130-099-456
Price$325
Order / More InfoCD87, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMay, A. E. et al. (1998) Urokinase receptor (CD87) regulates leukocyte recruitment via β2 integrins in vivo. J. Exp. Med. 188: 1029-1037. | Tarui, T. et al. (2001) Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction. J. Biol. Chem. 276: 3983-3990. | Ge, Y. et al. (2003) Urokinase plasminogen activator receptor (CD87): something old, something new. Lab. Hematol. 9 (2): 67-71.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies

© 1980 - 2024 Linscott's Directory, Linscott's USA. All rights reserved.