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Antigenic Specificity | CD66ace, Human |
Clone | REAL1206 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | phycoerythrin (PE) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD66ace Antibody, anti-human, PE, REAdye_lease™. Clone REAL1206 is an antibody fragment derived from the full CD66ace antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1206 recognizes the a, c and e epitopes of the human CD66 antigen. CD66 constitutes a gene family whose members belong to the Ig superfamily of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation. CD66a (CEACAM1), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
Immunogen | n/a |
Other Names | CEACAM1, CEACAM5, CEACAM6 |
Gene, Accession # | n/a |
Catalog # | 130-128-927 |
Price | $460 |
Order / More Info | CD66ace, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Gray-Owen, S. D. and Blumberg, R. S. (2006) CEACAM1: contact-dependent control of immunity. Nat. Rev. Immunol. 6: 433-446. | Guillaume, N. et al. (2011) CD66c expression in B-cell acute lymphoblastic leukemia: strength and weakness. Int J Lab Hematol 33 (1): 92-96. | Gebauer, F. et al. (2014) Carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1, 5 and 6 as biomarkers in pancreatic cancer. PLoS One 9 (11): e113023. |