CD66ace, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD66ace, Human
CloneREAL1206
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatphycoerythrin (PE) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionCD66ace Antibody, anti-human, PE, REAdye_lease™. Clone REAL1206 is an antibody fragment derived from the full CD66ace antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1206 recognizes the a, c and e epitopes of the human CD66 antigen. CD66 constitutes a gene family whose members belong to the Ig superfamily of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation. CD66a (CEACAM1), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogenn/a
Other NamesCEACAM1, CEACAM5, CEACAM6
Gene, Accession #n/a
Catalog #130-128-927
Price$460
Order / More InfoCD66ace, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGray-Owen, S. D. and Blumberg, R. S. (2006) CEACAM1: contact-dependent control of immunity. Nat. Rev. Immunol. 6: 433-446. | Guillaume, N. et al. (2011) CD66c expression in B-cell acute lymphoblastic leukemia: strength and weakness. Int J Lab Hematol 33 (1): 92-96. | Gebauer, F. et al. (2014) Carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1, 5 and 6 as biomarkers in pancreatic cancer. PLoS One 9 (11): e113023.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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