DAP12, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | DAP12, Human |
| Clone | REA900 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio Bright B515 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DAP12 Antibody, anti-human, Vio® Bright B515, REAfinity™. Clone REA900 recognizes the human DAP12 antigen, a transmembrane signaling polypeptide which consists of an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. DAP12 interacts with several members of the CD300 molecule-like family, CLECSF5 and Siglec14. The association of DAP12 with triggering receptor expressed on myeloid cells (TREM-1) and myeloid DAP12-associating lectin (MDL-1) plays a role in monocytic activation and inflammatory response. DAP12 is found in several tissues, but also in peripheral blood leukocytes. | Additional information: Clone REA900 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | KARAP, TYROBP |
| Gene, Accession # | Gene ID: 7305 |
| Catalog # | 130-122-804 |
| Price | $149 |
| Order / More Info | DAP12, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tomasello, E. et al. (2000) Association of signal-regulatory proteins beta with KARAP/DAP-12. Eur. J. Immunol. 30 (8): 2147-2156. | Gingras, M. S. et al. (2002) TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development. Mol. Immunol. 38 (11): 817-824. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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