CD335 (NKp46), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD335 (NKp46), Human
Clone9E2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
Formatbiotin conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFunctional assay
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DescriptionCD335 (NKp46) Antibody, anti-human, Biotin. Clone 9E2 recognizes the CD335 antigen, also known as NKp46. CD335 is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis and is exclusively expressed on CD3-CD56+ NK cells, suggesting it to be a universal marker for NK cells.
Immunogenn/a
Other NamesNCR1, LY94, NKp46
Gene, Accession #Gene ID: 9437
Catalog #130-125-207
Price$261
Order / More InfoCD335 (NKp46), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesPessino, A. et al. (1998) Molecular cloning of NKp46: A novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J. Exp. Med. 188: 953-960. | Moretta, L. and Moretta, A. (2004) Unravelling natural killer function: Triggering and inhibitory human NK receptors. EMBO J. 23: 255-259. | Sivori, S. et al. (2000) 2B4 functions as a co-receptor in human NK cell activation. Eur. J. Immunol. 30: 787-793. | Moretta, A. et al. (2001) Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197-223. | Lai, C. B. et al. (2012) Role of runt-related transcription factor 3 (RUNX3) in transcription regulation of natural cytotoxicity receptor 1 (NCR1/NKp46), an activating natural killer (NK) cell receptor. J. Biol. Chem. 287 (10): 7324-7334.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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