NKG2A/C/E, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | NKG2A/C/E, Mouse |
| Clone | REA1100 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | NKG2A/C/E Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA1100 recognizes the mouse NKG2A, NKG2C, and NKG2E antigen on a subset of natural killer (NK) and NK-T cells in most mouse strains, for example, AKR/J, BALB/c, C3H/He,C57BL/6, CBA/J, DBA/1, FVB/N, 129/Sv, NOD, SWR, and most DBA/2 substrains, but not DBA/2J. The C-type lectin-like NKG2 receptors form heterodimers of CD94 and one of several NKG2 family members, i.e., NKG2A (CD159a), NKG2C (CD159c), or NKG2E. CD94/NKG2 receptors monitor classical class I expression indirectly by means of the recognition of classical class I signal peptides. These signal peptides are processed to a nonameric peptide called Qdm that is presented to CD94/NKG2+ NK cells by a non-classical MHC class I molecule called Qa-1. CD94/NKG2 receptors equip NK cells with the capacity to detect cells with abnormal MHC class I expression, such as often results from viral infection or transformation. | Additional information: Clone REA1100 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD159a, CD159c, CD159e, NKG2A, KLRC1, NKG2C1, KLRC2, NKG2E, KLRC3 |
| Gene, Accession # | Gene ID: 16641 |
| Catalog # | 130-119-243 |
| Price | $160 |
| Order / More Info | NKG2A/C/E, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Lohwasser, S. et al. (1999) Cloning of murine NKG2A, B and C: second family of C-type lectin receptors on murine NK cells. Eur. J. Immunol. 29 (3): 755-761. | Silver, E. T. et al. (1999) Molecular cloning of mouse NKG2A and C. Immunogenetics 49 (7-8): 727-730. | Foley, B. et al. (2012) Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function. Blood 119 (11): 2665-2674. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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