TCRγ/δ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCRγ/δ, Mouse |
| Clone | GL3 |
| Host Species | Hamster |
| Reactive Species | mouse |
| Isotype | IgGκ |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCRγ/δ Antibody, anti-mouse, PE. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. The TCR consists of a α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). Clone GL3 reacts with a framework epitope of the γ/δ T-cell receptor. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T-cell receptor is present on a subset of T lymphocytes in peripheral blood, intestinal epithelium, lymph node, thymus and spleen. TCR γ/δ is involved in the recognition of certain bacterial, self-CD1 molecule, and tumor antigens bound to MHC class I. γ/δ T cells are mainly CD4 negative and CD8 negative. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, innate immune response for some tumor cells, and autoimmune disease. Antigen presentation by γ/δ T cells has been reported. |
| Immunogen | n/a |
| Other Names | TCRD, Tcrdelta, TCRGV1S1, TCRGV2S1, TCRGV3S1, TCRGV5S3, TCRG |
| Gene, Accession # | n/a |
| Catalog # | 130-104-012 |
| Price | $71 |
| Order / More Info | TCRγ/δ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Schmolka, N. et al. (2013) Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory γδ T cell subsets. Nat Immunol 14 (10): 1093-1100. | Prinz, I. et al. (2013) Functional development of γδ T cells. Eur. J. Immunol. 43 (8): 1988-1994. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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