CD134 (OX40), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD134 (OX40), Human antibody, protein, ELISA kits.
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| Antigenic Specificity | CD134 (OX40), Human |
| Clone | REA621 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD134 (OX40) Antibody, anti-human, Biotin, REAfinity™. Clone REA621 recognizes the CD134 (OX40) antigen, a member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. CD134 is a 50 kDa type I membrane glycoprotein expressed by activated T lymphocytes. The interaction of CD134 with OX40L has been implicated in T cell-dependent humoral response, regulation of primary T cell expansion, survival of T cells, size of the memory T cell pool, and regulation of tolerance in the CD4+ T cell compartment. It is reported, that CD134 activates NF-κB through its interaction with adaptor proteins TRAF2 and TRAF5. | Additional information: Clone REA621 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | OX-40, OX40 |
| Gene, Accession # | Gene ID: 7293 |
| Catalog # | 130-109-659 |
| Price | $87 |
| Order / More Info | CD134 (OX40), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Zaunders, J. J. et al. (2009) High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40). J Immunol 183: 2827-2836. | Croft, M. et al. (2009) The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol. Rev. 229 (1): 173-191. | Kawamata, S. et al. (1998) Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation. J. Biol. Chem. 273 (10): 5808-5814. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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