JAML, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | JAML, Mouse |
| Clone | REA862 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | JAML Antibody, anti-mouse, PE, REAfinity™. Clone REA862 recognizes the mouse JAML antigen, also known as AMICA1 or junctional adhesion molecule-like protein. JAML is a transmembrane protein, which consists of two extracellular immunoglobulin-like domains, a membrane-spanning region, and a cytoplasmic tail involved in activation signaling. JAML is found on γ/δ intraepithelial T cells. The costimulatory molecule JAML binds to its ligands Coxsackie virus and adenovirus receptor (CAR), that leads to cellular proliferation and cytokine and growth factor production. | Additional information: Clone REA862 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | AMICA1, junctional adhesion molecule-like |
| Gene, Accession # | Gene ID: 270152 |
| Catalog # | 130-114-488 |
| Price | $240 |
| Order / More Info | JAML, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Zen, K. et al. (2005) Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol. Biol. Cell 16 (6): 2694-2703. | Witherden, D. A. et al. (2010) The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science 329 (5996): 1205-1210. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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