CD186 (CXCR6), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD186 (CXCR6), Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD186 (CXCR6), Human |
| Clone | REA458 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD186 (CXCR6) Antibody, anti-human, PE, REAfinity™. Clone REA458 recognizes the human CD186 antigen, a multi-pass membrane protein which is also known as C-X-C chemokine receptor type 6 (CXCR6), STRL33, or bonzo. CD186 is expressed on a subset of type 1 polarized peripheral blood CD4+ and CD8+ T cells, γδ T cells, natural killer T cells, natural killer cells, monocytes, and B cells. It is induced in activated peripheral blood lymphocytes. The ligand of CD186 is the chemokine CXCL16. CD186 is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. | Additional information: Clone REA458 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | CXCR6, BONZO, STRL33, TYMSTR |
| Gene, Accession # | Gene ID: 10663 |
| Catalog # | 130-123-642 |
| Price | $114 |
| Order / More Info | CD186 (CXCR6), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wehr, A. et al. (2013) Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis. J Immunol 190 (10): 5226-5236. | Deng, H. K. et al. (1997) Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 388 (6639): 296-300. | Deng, L. et al. (2010) CXCR6/CXCL16 functions as a regulator in metastasis and progression of cancer. Biochim. Biophys. Acta 1806 (1): 42-49. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies