Siglec-F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Siglec-F, Mouse |
| Clone | REA798 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Siglec-F Antibody, anti-mouse, PE-Vio® 615, REAfinity™. Clone REA798 recognizes the mouse siglec-F antigen, also kown as Siglec-5, which belongs to the siglec family (sialic acid-binding immunoglobulin-type lectins). Siglecs are expressed on immune cells and are a subset of the I-type lectins. Siglec-F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. In mouse, siglec-F is an inhibitory receptor on eosinophils. | Additional information: Clone REA798 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | SIGLECF, SIGLEC5, mSiglec-F, Siglec-5 |
| Gene, Accession # | Gene ID: 233168 |
| Catalog # | 130-112-172 |
| Price | $485 |
| Order / More Info | Siglec-F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Tateno, H. et al. (2005) Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15 (11): 1125-1135. | Zhang, M. et al. (2007) Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 109 (10): 4280-4287. | Guo, J. P. et al. (2011) Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs. Am. J. Respir. Cell Mol. Biol. 44 (2): 238-243. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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