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Antigenic Specificity | MART-1, Human |
Clone | REA1093 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 200 µL |
Concentration | 1:50 |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MART-1 Antibody, anti-human, APC, REAfinity™. Clone REA1093 recognizes the human MART-1 protein, also known as Melan-A, which is an 18 kD transmembrane protein and expressed in cells of melanocytic lineage. MART-1 is expressed by a large proportion of melanomas and by melanoma cell lines. A fragment of the protein is bound by MHC class I complexes which present it to cytotoxic T cells of the immune system. | Additional Information: Clone REA1093 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | MLANA, MART1, Melan-A |
Gene, Accession # | Gene ID: 2315 |
Catalog # | 130-118-610 |
Price | $325 |
Order / More Info | MART-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Rimoldi, D. et al. (2001) Subcellular localization of the melanoma-associated protein Melan-AMART-1 influences the processing of its HLA-A2-restricted epitope. J. Biol. Chem. 276 (46): 43189-43196. | De Maziere, A. M. et al. (2002) The melanocytic protein Melan-A/MART-1 has a subcellular localization distinct from typical melanosomal proteins. Traffic 3 (9): 678-693. |