IL-22, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-IL-22, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IL-22, Human |
| Clone | REA466 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-22 Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA466 recognizes the human interleukin-22 (IL-22) antigen, a secreted molecule which belongs to the IL-10 family of cytokines. IL-22 is produced by immune cells, including T helper cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in particular epithelial cells, keratinocytes, and hepatocytes. It plays an important role in host defense at mucosal surfaces as well as in tissue repair. Although IL-22 is beneficial to the host in many infectious and inflammatory disorders, depending on the target tissue it can be pathogenic due to its inherent pro-inflammatory properties, which are further enhanced when IL-22 is released together with other pro-inflammatory cytokines, in particular IL-17. | Additional information: Clone REA466 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL-TIF, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, IL-21 |
| Gene, Accession # | Gene ID: 50616 |
| Catalog # | 130-130-561 |
| Price | $400 |
| Order / More Info | IL-22, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Dumoutier, L. et al. (2000) Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor. Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10144-10149. | Rutz, S. et al. (2013) IL-22, not simply a T?17 cytokine. Immunol. Rev. 275 (1): 116-132. | Xie, M. H. et al. (2013) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275 (40): 31335-31339. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies