CD207 (Langerin), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD207 (Langerin), Mouse |
| Clone | REA822 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD207 (Langerin) Antibody, anti-mouse, Biotin, REAfinity™. Clone REA822 recognizes the mouse CD207 antigen, also known as Langerin, which is a 48 kDa transmembrane type II C-type lectin containing a single carbohydrate recognition domain in its extracellular region. Langerin is specifically expressed on epidermal Langerhans cells and dermal CD103+ dendritic cells. It displays Ca 2)+-dependent binding specificity for mannose, N-acetyl-glucosamine, and fucose and is involved in antigen recognition, uptake, and transport to the Birbeck granules, whose formation is dependent on Langerin expression. The CD207 epitope shows trypsin as well as collagenase sensitivity. | Additional information: Clone REA822 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Langerin |
| Gene, Accession # | Gene ID: 246278 |
| Catalog # | 130-113-050 |
| Price | $64 |
| Order / More Info | CD207 (Langerin), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Valladeau, J. et al. (2002) Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues. J Immunol 168 (2): 782-792. | Idoyaga, J. et al. (2008) Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J Immunol 180 (6): 3647-3650. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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