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Antigenic Specificity | CD44H, Rat |
Clone | REA505 |
Host Species | Recombinant Human |
Reactive Species | rat |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD44H Antibody, anti-rat, PE, REAfinity™. Clone REA505 recognizes the rat CD44H antigen, a transmembrane glycoprotein, also known as homing-associated cell adhesion molecule (H-CAM) or phagocytic glycoprotein-1 (Pgp-1). CD44H belongs to the CD44 group, that encompasses several isoforms expressed in a variety of tissues. It is highly expressed on hematopoietic and non-hematopoietic cells. All isoforms are encoded by the same gene on chromosome 11 and are formed by alternative splicing of their mRNA. CD44 isoforms belong to the family of cell adhesion molecules and to the sub-family of the hyaladherins in consideration of their affinity for hyaluronate and their structural homology with the cartilage link protein. The standard form of CD44, CD44H, exhibits a high affinity for hyaluronate, plays a role in the uptake and degradation of this glycosaminoglycan, and participates in cell locomotion in its presence. | Additional information: Clone REA505 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CD44s, CD44A, METAA, RHAMM, CD44, Pgp-1, H-CAM, CD44st, CD44std |
Gene, Accession # | Gene ID: 25406 |
Catalog # | 130-107-855 |
Price | $43 |
Order / More Info | CD44H, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Zheng, Z. et al. (1995) Monoclonal antibodies to CD44 and their influence on hyaluronan recognition. J. Cell Biol. 130 (2): 485-495. | Thomas, L. (1993) CD44, the hyaluronic acid cell receptor. Its role in neoplastic invasion and metastatic dissemination. Bull Cancer 80 (10): 833-844. |