Plexin-B2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-Plexin-B2, Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Plexin-B2, Mouse |
| Clone | REA445 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Plexin-B2 Antibody, anti-mouse, PE, REAfinity™. Clone REA445 recognizes the mouse Plexin-B2 antigen, a Single-pass type I membrane protein which belongs to the semaphorin receptor family, B subfamily. Plexin-B2 is expressed in the nervous system and on other cells including cells of the immune system. It is expressed on T cells and T-dependent germinal center B cells. Expression is also found on macrophages, conventional dendritic cells and plasmacytoid dendritic cells. Plexin-B2 plays an important role in cell-cell signaling, axon guidance, invasive growth and cell migration. It has several semaphorin ligands including Semaphorin-3E, Semaphorin-4A, Semaphorin-4C, and Semaphorin-4D (CD100). Binding to class 4 semaphorins promotes the downstream activation of RHOA and phosphorylation of ERBB2. During skin damage repairs, CD100 interacts with Plexin-B2 on gamma delta T cells to play a role in the healing process. | Additional information: Clone REA445 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Plxnb2, Debt |
| Gene, Accession # | Gene ID: 140570 |
| Catalog # | 130-106-408 |
| Price | $46 |
| Order / More Info | Plexin-B2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Witherden, D. A. et al. (2012) The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. Immunity 37 (2): 314-325. | Deng, S. et al. (2007) Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J. Neurosci. 27 (23): 6333-6347. | Saha, B. et al. (2012) Plexin-B2 regulates the proliferation and migration of neuroblasts in the postnatal and adult subventricular Zone. J. Neurosci. 32 (47): 16892-16905. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG