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Antigenic Specificity | NK1.1, Mouse |
Clone | REA1162 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NK1.1 Antibody, anti-mouse, PE, REAfinity™. Clone REA1162 recognizes the mouse NK1.1 antigen, a single-pass type II membrane protein also known as CD161 or killer cell lectin-like receptor subfamily B member 1. NK1.1 is expressed by natural killer cells and a subset of T cells in the mouse strains C57BL/6, FVB/N, and NZB, but not in the mouse strains AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. It plays a stimulatory role on natural killer cells cytotoxicity. Activation by cross-linking of the receptor induces Ca 2)+ mobilization and interferon-gamma production. | Additional information: Clone REA1162 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | NKR-P1 40, CD161c, Ly-55c, NK1.1, NKR-P1.9, NKR-P1C |
Gene, Accession # | Gene ID: 17059 |
Catalog # | 130-120-497 |
Price | $240 |
Order / More Info | NK1.1, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Giorda, R. et al. (1992) Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1. J Immunol 149 (6): 1957-1963. | Stenstrom, M. et al. (2005) Natural killer T-cell populations in C57BL/6 and NK1.1 congenic BALB.NK mice-a novel thymic subset defined in BALB.NK mice. Immunology 114 (3): 336-345. | Ruiz, A. L. et al. (2014) NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response. Nat Commun. 5: 5150. |