Oct-2, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-Oct-2, Human/Mouse antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Oct-2, Human/Mouse |
| Clone | REA251 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | Vio B515 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Oct-2 Antibody, anti-human/mouse, Vio® B515, REAfinity™. Clone REA251 recognizes the Octamer-binding protein 2 (Oct-2) antigen, a transcription factor also known as POU domain class 2 transcription factor 2 (POU2F2). Oct-2 is expressed primarily in B lymphocytes and the developing central nervous system. It regulates gene transcription in a number of tissues in addition to activating immunoglobulin gene expression for normal humoral responses to T-dependent and T-independent antigens. Oct-2 binds to conserved sites in immunoglobulin variable gene promoters, several immunoglobulin gene enhancers and to sites in the promoters of other genes whose expression is B cell restricted. Once bound to a promoter, Oct-2 facilitates the assembly of the transcription initiation complex. | Additional information: Clone REA251 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | POU2F2, OTF-2, POU2F2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding transcription factor 2, OTF-2, Octamer-binding protein 2 |
| Gene, Accession # | Gene ID: 5452 |
| Catalog # | 130-130-891 |
| Price | $385 |
| Order / More Info | Oct-2, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Humbert, P. O. and Corcoran, L. M. (1997) Oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function. J Immunol 159 (11): 5273-5284. | Muller-Immergluck, M. M. et al. (1990) Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells. EMBO J. 9 (5): 1625-1634. | Clerc, R. G. et al. (1988) The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev. 12: 1570-1581. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG