CD8b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD8b, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD8b, Human |
| Clone | REA715 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | VioBlue conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD8b Antibody, anti-human, VioBlue®, REAfinity™. Clone REA715 recognizes the human CD8b antigen, a single-pass type I membrane protein and member of the immunoglobulin superfamily, also known as T cell surface glycoprotein Lyt-3. The CD8 glycoprotein is expressed by thymocytes, mature T cells, and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex class I antigens and in signal transduction during the course of T cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. Most of peripheral blood CD8+ T lymphocytes express the CD8a/CD8b heterodimer, while CD8+CD16+ natural killer cells and CD8+ T cell receptor γ/δ+ T lymphocytes express only the CD8a/CD8a homodimer. CD8b can therefore be used to selectively bind to CD8+ T cells while excluding CD8+ NK cells. | Additional information: Clone REA715 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CD8 beta chain, CD8 b chain, CD8b |
| Gene, Accession # | Gene ID: 926 |
| Catalog # | 130-110-515 |
| Price | $345 |
| Order / More Info | CD8b, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Norment, A. M. et al. (1988) A second subunit of CD8 is expressed in human T cells. EMBO J. 7 (11): 3433-3439. | Baume, D. M. et al. (1990) Differential expression of CD8 alpha and CD8 beta associated with MHC-restricted and non-MHC-restricted cytolytic effector cells. Cell. Immunol. 131 (2): 352-365. | Terry, L. A. et al. (1990) Differential expression and regulation of the human CD8 alpha and CD8 beta chains. Tissue Antigens 35 (2): 82-91. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies