Slan (M-DC8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Slan (M-DC8), Human |
| Clone | REA1050 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Slan (M-DC8) Antibody, anti-human, APC, REAfinity™. Clone REA1050 recognizes the human 6-sulfo LacNAc (Slan) (M-DC8) antigen, which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14low monocytes. Slan (M-DC8)+ cells constitute 0.5-2% of all PBMCs with similar frequencies among mononuclear cells from cord blood. | Additional information: Clone REA1050 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | SELPLG, CD162, CLA, PSGL-1, PSGL1 |
| Gene, Accession # | Gene ID: 6404 |
| Catalog # | 130-117-919 |
| Price | $325 |
| Order / More Info | Slan (M-DC8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Schakel, K. et al. (1998) A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur. J. Immunol. 28: 4084-4093. | de Baey, A. et al. (2001) Phenotype and function of human dendritic cells derived from M-DC8+ monocytes. Eur. J. Immunol. 31: 1646-1655. | Schakel, K. et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289-301. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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