Helios, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Helios, Human/Mouse |
| Clone | REA829 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Helios Antibody, anti-human/mouse, PE, REAfinity™. Clone REA829 recognizes mouse and human Helios, which is a zinc-finger transcription factor of the Ikaros family. As well as Ikaros and Aiolos, Helios functions as an important regulator of lymphoid development and differentiation and is involved in the control of gene expression. Helios is found on the earliest haematopoietic sites of the embryo, in adult haemopoietic stem cells, and on regulatory T cells. | Additional information: Clone REA829 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IKZF2, ANF1A2, ZNF1A2, ZNFN1A2 |
| Gene, Accession # | Gene ID: 22807 |
| Catalog # | 130-112-819 |
| Price | $121 |
| Order / More Info | Helios, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kelley, C. M. et al. (1998) Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 8 (9): 508-515. | Rebollo, A. et al. (2003) Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies. Immunol. Cell Biol. 81: 171-175. | Thornton, A. M. et al. (2010) Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. Curr. Biol. 184: 3433-3441. | Gottschalk, R. A. et al. (2012) Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J Immunol 188: 976-980. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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