CD11b, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD11b, Human/Mouse |
| Clone | M1/70.15.11.5 |
| Host Species | Rat |
| Reactive Species | human, mouse, nonhuman primate |
| Isotype | IgG2bκ |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD11b Antibody, anti-human/mouse, PE. CD11b, also known as Mac-1 α or integrin αM chain, is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain. In mice, the CD11b antigen is expressed on monocytes/macrophages and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5+ B-1 cells, and subsets of dendritic cells. The monoclonal M1/70.15.11.5 antibody recognizes the human, mouse, and non-human primate CD11b antigen. |
| Immunogen | n/a |
| Other Names | ITGAM, CR3A, Mac-1 α, MAC1A, MO1A, SLEB6, integrin αM |
| Gene, Accession # | Gene ID: 3684 |
| Catalog # | 130-113-235 |
| Price | $310 |
| Order / More Info | CD11b, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Lebson, L. et al. (2010) Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. J. Neurosci. 30 (29): 9651-9658. | Liu, T. et al. (2014) Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation. Sci Rep 4: 4833. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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