Mucin-5AC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Mucin-5AC, Human |
| Clone | REAL915 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mucin-5AC Antibody, anti-human, PE, REAdye_lease™. Clone REAL915 is an antibody fragment derived from the full Mucin-5AC antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL915 recognizes the human Mucin-5AC, also known as MUC 5AC, a glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Mucin-5AC is highly expressed in surface mucosal cells of the respiratory tract, stomach epithelia, in Barrett's esophagus epithelium and in the proximal duodenum. It is overexpressed in a number of carcinomas, has been linked to mucus hypersecretion in the respiratory tract and is associated to chronic obstructive pulmonary disease (COPD). | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | MUC-5AC, MUC5AC, MUC5, Gastric mucin, TBM (Tracheobronchial mucin), major airway glyoprotein, Mucin-5 subtype AC, tracheobronchia |
| Gene, Accession # | n/a |
| Catalog # | 130-127-552 |
| Price | $460 |
| Order / More Info | Mucin-5AC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kocer, B. et al. (2002) Expression of MUC5AC in colorectal carcinoma and relationship with prognosis. Pathol Int. 52 (7): 470-477. | Terada, T. (2013) An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: II. Expression of MUC1, MUC2, MUC5AC, and MUC6 in normal mucosa and in 42 cases. Int J Clin Exp Pathol 6 (4): 613-621. | Kaur, S. et al. (2017) A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. Am J Gastroenterol. 112 (1): 172-183. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG