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Antigenic Specificity | ELK-1 pS383, Human |
Clone | REA896 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ELK-1 pS383 Antibody, anti-human, FITC, REAfinity™. Clone REA896 recognizes the human transcription factor ELK-1, also known as ETS domain-containing protein ELK-1. ELK-1 is a member of the E twenty-six (Ets) oncogene family that consists of nuclear phosphoproteins, which are involved in many processes, e.g., differentiation, growth, and survival of cells, hematopoiesis, angiogenesis, wound healing, cancer, and inflammation. ELK-1 is a target of ERK1 and ERK2, which are both members of protein kinases, but also of JNK and p38 MAPK, which are all involved in diverse physiopathological forms of neuronal plasticity. ELK-1 is mainly found in brain, and it is strongly expressed in neurons. | Additional information: Clone REA896 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ELK1 |
Gene, Accession # | Gene ID: 2002 |
Catalog # | 130-114-896 |
Price | $93 |
Order / More Info | ELK-1 pS383, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Gille, H. et al. (1995) ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14 (5): 951-962. | Sharrocks, A. D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2 (11): 827-837. | Besnard, A. et al. (2011) Elk-1 a transcription factor with multiple facets in the brain. Front. Neurosci. 5: 35. |