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Antigenic Specificity | Cytokeratin 8, Human |
Clone | REA885 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 8 Antibody, anti-human, APC, REAfinity™. Clone REA885 recognizes the human type II keratin protein cytokeratin 8, an intermediate filament protein, which is found in epithelial and carcinoma cells. In adult tissues cytokeratin 8 is expressed as a heterodimer with cytokeratin 18. | Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions, and are involved in intracellular signaling pathways. | Additional information: Clone REA885 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Cytokeratin-8, CK-8, Keratin-8 |
Gene, Accession # | Gene ID: 3856 |
Catalog # | 130-114-648 |
Price | $142 |
Order / More Info | Cytokeratin 8, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Leube, R. E. et al. (1986) Cytokeratin expression in simple epithelia. III. Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences in vitro and in situ. Differentiation 33 (1): 69-85. | Krauss, S. et al. (1990) Organization and sequence of the human gene encoding cytokeratin 8. Gene 86 (2): 241-249. | Moll, R. et al. (2008) The human keratins: biology and pathology. Histochem. Cell Biol. 129 (6): 705-733. |