CD99, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD99, Human |
| Clone | 3B2/TA8 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2aκ |
| Format | biotin conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD99 Antibody, anti-human, Biotin. Clone 3B2/TA8 recognizes the human CD99 antigen, a 32 kDa type I single chain transmembrane sialoglycoprotein which is also known as E2 antigen or MIC2. The expression level of CD99 is particularly high in thymocytes, T cells, T cell leukemias and lymphomas, subsets of mature plasma cells in the medullary cord of reactive lymph nodes, pancreatic islet cells, granulosa cells of the ovary, Sertoli cells of the testes, but absent on granulocytes. It is involved in T cell-adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane and it acts at the same site as, but independently of, PECAM1. |
| Immunogen | n/a |
| Other Names | HBA71, MIC2, MIC2X, MIC2Y, MSK5X |
| Gene, Accession # | Gene ID: 4267 |
| Catalog # | 130-106-235 |
| Price | $264 |
| Order / More Info | CD99, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Schenkel, A. R. et al. (2002) CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat Immunol 3 (2): 143-150. | Gelin, C. et al. (1989) The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product. EMBO J. 8 (11): 3253-3259. | Edlund, K. et al. (2012) CD99 is a novel prognostic stromal marker in non-small cell lung cancer. Int. J. Cancer 131 (10): 2264-2273. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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