Ly-49D, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityLy-49D, Mouse
CloneREAL452
Host SpeciesRecombinant Human
Reactive Speciesmouse
Isotypen/a
FormatVioBlue conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionLy-49D Antibody, anti-mouse, VioBlue®, REAlease®. Clone REAL452 is an antibody fragment derived from the full Ly-49D antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL452 recognizes Ly49D, a type II transmembrane NK-cell receptor belonging to the Ly49 family. Members of Ly49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. Ly49D is a prototypic activating member of Ly49 family and in contrast to inhibitory members, lacks a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM). A positive signal is initiated by interaction of Ly49D with immunoreceptor tyrosine-based activating motif (ITAM) containing transmembrane adapter DAP12. Expression of Ly49D is strain restricted and is found on subsets of NK cells in C57BL/6, C3H/He and SJL but not in BALB/c, DBA/2, AKR and CBA/J mice. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.
Immunogenn/a
Other NamesKlra4, Chok, Klra32, Klra33, Ly-49d
Gene, Accession #n/a
Catalog #130-123-065
Price$154
Order / More InfoLy-49D, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific Referencesn/a
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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