CD56, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD56, Human
CloneREA196
Host SpeciesRecombinant Human
Reactive Specieshuman, nonhuman primate
IsotypeIgG1
FormatPE-Vio 615 conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD56 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA196 recognizes the human CD56 antigen, a glycoprotein of the Ig-superfamily, also known as neural cell adhesion molecule (NCAM), which is expressed in blood on practically all resting and activated NK cells and on a minor subset of CD3+ T cells. CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal-derived tumors, myelomas, and myeloid leukemias also express CD56. | Additional information: Clone REA196 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesNCAM1, MSK39, NCAM
Gene, Accession #Gene ID: 4684
Catalog #130-114-550
Price$350
Order / More InfoCD56, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesCamp, B. V. et al. (1990) Plasma cells in multiple myeloma express a natural killer cell- associated antigen: CD56 (NKH-1; Leu-19). Blood 76: 377-382. | Vivier, E. et al. (2018) Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell 175 (7): 1731-1743. | Boin, F. et al. (2017) Flow cytometric discrimination of seven lineage markers by using two fluorochromes. PLoS One 12 (11): . | Petty, R. D. et al. (2016) MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: potential diagnostic biomarkers in natural killer (NK) cells of patients with chronic fatigue syndrome (CFS)/ myalgic encephalomyelitis (ME). PLoS One 11: e0150904. | Dong, P. et al. (2017) Simultaneous detection of decidual Th1/Th2 and NK1/NK2 immunophenotyping in unknown recurrent miscarriage using 8-color flow cytometry with FSC/Vt extended strategy. Biosci. Rep. 37 (3): . | Cante-Barrett, K. et al. (2017) Loss of CD44dim expression from early progenitor cells marks T-cell lineage commitment in the human thymus. Front Immunol 8: 32. | Croci, S. et al. (2018) Higher frequencies of lymphocytes expressing the natural killer group 2D receptor in patients with Behcet disease. Front Immunol 9: 2157. | Delso-Vallejo, M. et al. (2017) Influence of irradiated peripheral blood mononuclear cells on both ex vivo proliferation of human natural killer cells and change in cellular property. Front Immunol 8: . | Grant, M. D. et al. (2018) Natural Killer Cells Adapt to Cytomegalovirus Along a Functionally Static Phenotypic Spectrum in Human Immunodeficiency Virus Infection. Front Immunol 9: 2494. | Popkin, D. L. et al. (2018) In vitro evidence that combination therapy with CD16-bearing NK-92 cells and FDA-approved Alefacept can selectively target the latent HIV reservoir in CD4+ CD2hi memory T cells. Front Immunol 9: 2552. | Soldierer, M. et al. (2022) Genetic Engineering and Enrichment of Human NK Cells for CAR-Enhanced Immunotherapy of Hematological Malignancies, Front Immunol 13: doi: 10.3389/fimmu.2022.847008. | Veluchamy, J. et al. (2017) In vivo efficacy of umbilical cord blood stem cell-derived NK cells in the treatment of metastatic colorectal cancer. Front Immunol 8: 87.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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