CD81, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD81, Human |
| Clone | REA513 |
| Host Species | Recombinant Human |
| Reactive Species | human, nonhuman primate |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD81 Antibody, anti-human, PE, REAfinity™. Clone REA513 recognizes the human CD81 antigen, a multi-pass membrane protein also known as TAPA-1. It is a member of the tetraspanin family including, for example, CD9, CD37, CD53, CD63, CD82, and CD151. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. The 26 kDa cell surface protein is involved in adhesion, activation, proliferation, and differentiation of B cells, T cells, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. Similarly on T cells CD81 associates with CD4 and CD8 and provides a costimulatory signal with CD3. CD81 is expressed by epithelial and endothelial cells, T and B cells, as well as natural killer (NK) cells. | Additional information: Clone REA513 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | CVID6, S5.7, TAPA1, TSPAN28 |
| Gene, Accession # | Gene ID: 975 |
| Catalog # | 130-118-342 |
| Price | $315 |
| Order / More Info | CD81, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Levy, S. (1998) CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu. Rev. Immunol. 16: 89-109. | Wright, M. D. et al. (1994) The ins and outs of the transmembrane 4 superfamily. Immunol. Today 15 (12): 588-594. | Levy, S. (1991) Structure and membrane topology of TAPA-1. J. Biol. Chem. 266 (22): 14597-14602. | Oren, R. (1990) TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. Mol. Cell. Biol. 10 (8): 4007-4015. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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