CD102 (ICAM-2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD102 (ICAM-2), Human
CloneREA878
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD102 (ICAM-2) Antibody, anti-human, PE, REAfinity™. Clone REA878 recognizes the human CD102 antigen, a type I transmembrane glycoprotein with two immunoglobulin-like domains. CD102, also known as ICAM-2, is a member of the intercellular adhesion molecule (ICAM) family, that binds to leukocyte integrin, lymphocyte function-associated antigen-1 (LFA-1), dendritic cell-specific antigen, ICAM-grabbing non-integrin (DC-SIGN) protein and macrophage-1 antigen (MAC-1). CD102 is found on vascular endothelial cells, monocytes, platelets and different populations of lymphocytes. | CD102 is involved in lymphocyte recirculation and induces essential adhesive cell interactions, which are important for immune response and surveillance. | Additional information: Clone REA878 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesICAM-2
Gene, Accession #Gene ID: 3384
Catalog #130-114-304
Price$315
Order / More InfoCD102 (ICAM-2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesStaunton, D. E. et al. (1989) Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 339 (6219): 61-64. | Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155. | Weber, K. S. et al. (2004) Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN. Inflammation 28 (4): 177-188.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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