CD72, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD72, Human |
| Clone | REA231 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD72 Antibody, anti-human, FITC, REAfinity™. Clone REA231 recognizes CD72, a 45 kDa type II membrane protein with a C-type lectin-like domain. Expression of CD72 is found on most B-lineage cells, follicular dendritic cells, mast cells, and liver Kupffer cells. CD72 is recognized as negative regulator of B cell receptor (BCR) signaling, as well as regulating mast cell growth and differentiation via KIT activation. The inhibitory role of CD72 is exerted via the ITIM sequence in the cytoplasmic tail. | Additional information: Clone REA231 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | CD72b, Lyb-2 |
| Gene, Accession # | Gene ID: 971 |
| Catalog # | 130-132-449 |
| Price | $297 |
| Order / More Info | CD72, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kataoka, T. R. et al. (2010) CD72 negatively regulates KIT-mediated responses in human mast cells. J Immunol 184: 2468-2475. | Li, D. H. et al. (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J Immunol 176: 5321-5328. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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