CD70, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD70, Human
CloneREA292
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatPE-Vio 770 conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD70 Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA292 recognizes the human CD70 antigen, a 50 kDa type II transmembrane glycoprotein also known as CD27 ligand (CD27L) or tumor necrosis factor ligand superfamily member 7 (TNFSF7). CD70 is a member of the TNF superfamily and is expressed by activated mouse T, B, and NK lymphocytes, activated plasmacytoid dendritic cells (pDCs), chronic B cell lymphocytic leukemia, and large B cell lymphomas. It interacts with CD27, its ligand on T cells, in order to promote T-B cell cross-stimulation and co-stimulates B cell proliferation and immunoglobulin production. It also plays a role in the pDC-induced B cell differentiation. | Additional information: Clone REA292 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesCD27L, CD27LG, TNFSF7
Gene, Accession #Gene ID: 970
Catalog #130-104-310
Price$350
Order / More InfoCD70, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBowman, M. R. et al. (1994) The cloning of CD70 and its identification as the ligand for CD27. J Immunol 152 (4): 1756-1761. | Goodwin, R. G. et al. (1993) Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor. Cell 73 (3): 447-456.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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