TCR Vβ9, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCR Vβ9, Mouse |
| Clone | REA727 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCR Vβ9 Antibody, anti-mouse, APC, REAfinity™. Clone REA727 recognizes the mouse V beta 9 T cell receptor (TCR Vβ9). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCR Vβ9 is a variant of the TCR β chain and is expressed on mouse strains with the b haplotype (e.g. C57BL/6) in the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g. Balb/c) or c (e.g. SJL, NOD) haplotype. Murine Vβ9+ cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens. | Additional information: Clone REA727 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCR Vb9 |
| Gene, Accession # | Gene ID: 100124665 |
| Catalog # | 130-111-058 |
| Price | $88 |
| Order / More Info | TCR Vβ9, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Behlke, M. A. et al. (1986) Murine T-cell receptor mutants with deletions of beta-chain variable region genes. Proc. Natl. Acad. Sci. U.S.A. 83 (3): 767-771. | Haggi, T. M. et al. (1989) RIII S/J (H-2r). An inbred mouse strain with a massive deletion of T cell receptor V beta genes. J. Exp. Med. 169 (6): 1903-1909. | Tomonari, K. et al. (1990) Correlation between the V beta 4+ CD8+ T-cell population and the H-2d haplotype. Immunogenetics 31 (5-6): 333-339. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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