CD101, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD101, Human |
| Clone | REA954 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD101 Antibody, anti-human, PE, REAfinity™. Clone REA954 recognizes the human CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5-30% of FoxP3+ Treg cells in peripheral blood. The interaction of CD101 with clone REA954 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies. | Additional information: Clone REA954 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | EWI-101, IGSF2, V7, p126 |
| Gene, Accession # | Gene ID: 9398 |
| Catalog # | 130-115-902 |
| Price | $119 |
| Order / More Info | CD101, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Rivas, A. et al. (1995) V7, a novel leukocyte surface protein that participates in T cell activation. J Immunol 154: 4423-4433. | Soares, L. R. et al. (1998) V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca2+ flux and nuclear factor of activated T cell nucleartranslocation. J Immunol 161: 209-217. | Bouloc, A. et al. (2000) Triggering CD101 molecule on human cutaneous dendritic cells inhibits T cell proliferation via IL-10 production. Eur. J. Immunol. 30: 3132-3139. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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