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Antigenic Specificity | CD25, Human |
Clone | REA570 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 615 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD25 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA570 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). It associates with IL-2 receptor β (CD122) and γ chains (CD132) to form a high affinity IL-2R complex. CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4+ regulatory T cells. Clone REA570 recognizes epitope region A. | Additional information: Clone REA570 displays negligible binding to Fc receptors |
Immunogen | n/a |
Other Names | IL2RA, IDDM10, IL2R, TCGFR, p55, Tac |
Gene, Accession # | Gene ID: 3559 |
Catalog # | 130-123-045 |
Price | $154 |
Order / More Info | CD25, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Lee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J Immunol 189 (6): 2712-2716. | Piccirillo, C. A. et al. (2006) Development and function of naturally occurring CD4+ CD25+ regulatory T cells. J. Leukoc. Biol. 3: 458-470. | Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146 (3): 248-261. |