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Antigenic Specificity | TCRγ/δ, Rat |
Clone | REA547 |
Host Species | Recombinant Human |
Reactive Species | rat |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCRγ/δ Antibody, anti-rat, APC, REAfinity™. Clone REA547 recognizes the rat TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α- and a β-chain (TCRα/β) or a γ- and a δ-chain (TCRγ/δ). The γ and δ TCR-chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ-chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules. | Additional information: Clone REA547 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | gd TCR |
Gene, Accession # | Gene ID: 24821, 290108 |
Catalog # | 130-108-762 |
Price | $59 |
Order / More Info | TCRγ/δ, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Kuhnlein, P. et al. (1994) Identification and characterization of rat gamma/delta T lymphocytes in peripheral lymphoid organs, small intestine, and skin with a monoclonal antibody to a constant determinant of the gamma/delta T cell receptor. J Immunol 153 (3): 979-986. | Chien, Y. H. et al. (1996) Recognition by gamma/delta T cells. Annu. Rev. Immunol. 14: 511-532. | Smith-Garvin, J. E. et al. (2009) T cell activation. Annu. Rev. Immunol. 27: 591-619. |