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Antigenic Specificity | CD336 (NKp44), Human |
Clone | REA1163 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD336 (NKp44) Antibody, anti-human, Biotin, REAfinity™. Clone REA1163 recognizes the human CD336 antigen, also known as NKp44. CD336 is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in natural killer (NK) cells. CD336 is directly involved in target cell recognition and lysis and is only expressed by activated NK cells, e.g., NK cells cultured in the presence of interleukin 2 (IL-2). Freshly isolated, resting NK cells do not express CD336. | Additional information: Clone REA1163 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | NCR2, LY95, NKp44 |
Gene, Accession # | Gene ID: 9436 |
Catalog # | 130-120-362 |
Price | $270 |
Order / More Info | CD336 (NKp44), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Vitale, M. et al. (1998) NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J. Exp. Med. 187: 2065-2072. | Sivori, S. et al. (2000) 2B4 functions as a co-receptor in human NK cell activation. Eur. J. Immunol. 30: 787-793. | Moretta, A. et al. (2001) Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197-223. | Chaput, N. et al. (2013) Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR+ NK cell levels correlate with disease outcome. Oncoimmunology 2 (2): e23080. |