CD310 (VEGFR-3), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD310 (VEGFR-3), Mouse |
| Clone | REA834 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD310 (VEGFR-3) Antibody, anti-mouse, PE, REAfinity™. Clone REA834 recognizes the mouse CD310 antigen, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4 or VEGFR-3. During early embryogenesis all endothelial cells express CD310, while in the adult tissues CD310 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. CD310 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for CD310. | Additional information: Clone REA834 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | FLT4, Chy, FLT-4, VEGFR-3 |
| Gene, Accession # | Gene ID: 14257 |
| Catalog # | 130-112-772 |
| Price | $72 |
| Order / More Info | CD310 (VEGFR-3), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Galland, F. et al. (1992) Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene. Genomics 13 (2): 475-478. | Kubo, H. et al. (2000) Involvement of vascular endothelial growth factor receptor-3 in maintance of integrity of endothelial cell lining during tumor angiogenesis. Blood 2 (96): 546-553. | Zhang, L. et al. (2010) VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 20 (12): 1319-1331. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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