CD14, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD14, Mouse
CloneREA934
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionCD14 Antibody, anti-mouse, FITC, REAfinity™. Clone REA934 recognizes the mouse CD14 antigen, a cell surface glycoprotein preferentially expressed on monocytes/macrophages, but also on granulocytes, dendritic cells, Kupffer cells, and hepatocytes. In association with toll-like receptors TLR 4 and MD-2, CD14 is a highly specific co-receptor for bacterial lipopolysaccharide (LPS) and for a variety of other pathogen-associated molecular patterns of microbial sources. The association of CD14 with LPS is mediated by the LPS-binding protein (LBP). | Additional information: Clone REA934 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesLPS receptor
Gene, Accession #Gene ID: 12475
Catalog #130-115-557
Price$54
Order / More InfoCD14, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesFerrero, E. et al. (1990) CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes. J Immunol 145 (1): 331-336. | Gangloff, S. C. et al. (2005) Influence of CD14 on ligand interactions between lipopolysaccharide and its receptor complex. J Immunol 175 (6): 3940-3945. | Drage, M. G. et al. (2009) TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis. Cell. Immunol. 258 (1): 29-37.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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