MRP14, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | MRP14, Human |
| Clone | REA859 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MRP14 Antibody, anti-human, FITC, REAfinity™. Clone REA859 recognizes the human MRP14 antigen, a calcium- and zinc-binding protein also known as S100A9 or calgranulin-B. MRP14 is mainly expressed in myeloid cells, e.g. MDSCs, neutrophils, and monocytes, and plays an important role in the regulation of inflammatory processes and immune response. MRP14 is involved in neutrophil chemotaxis and adhesion, and is able to increase the bactericidal activity of neutrophils. | Additional information: Clone REA859 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | S100-A9, Calgranulin-B, MRP-14, p14 |
| Gene, Accession # | Gene ID: 6280 |
| Catalog # | 130-114-706 |
| Price | $93 |
| Order / More Info | MRP14, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Odink, K. et al. (1987) Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330 (6143): 80-82. | Rammes, A. et al. (1997) Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J. Biol. Chem. 272 (14): 9496-9502. | Loser, K. et al. (2010) The toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells. Nat Med 16 (6): 713-717. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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