HLA-ABC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityHLA-ABC, Human
CloneREAL286
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatallophycocyanin (APC) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionHLA-ABC Antibody, anti-human, APC, REAdye_lease™. Clone REAL286 is an antibody fragment derived from the full HLA-ABC antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL286 recognizes a monomorphic epitope on MHC (human major histocompatibility complex) class I molecules, HLA A, B, and C. MHC class I molecules are expressed by all human nucleated cells and are involved in presentation of peptide ligands on the cell surface for recognition by cytotoxic T cells. HLA-ABC plays an deciding role in cell-mediated immune response and tumor surveillance. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
Immunogenn/a
Other NamesHLA-A, HLA-B, HLA-C, AS, SPDA1, D6S204, HLA-JY3, HLC-C, PSORS
Gene, Accession #n/a
Catalog #130-121-328
Price$490
Order / More InfoHLA-ABC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMelsted, W. N. et al. (2017) HLA class Ia and Ib molecules and FOXP3+ TILs in relation to the prognosis of malignant melanoma patients. Clin. Immunol. 183: 191-197. | Chaganty, B. K. et al. (2015) Trastuzumab upregulates expression of HLA-ABC and T cell costimulatory molecules through engagement of natural killer cells and stimulation of IFNγ secretion. Oncoimmunology 5 (4): e1100790.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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