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Antigenic Specificity | CD30, Human |
Clone | REA1085 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD30 Antibody, anti-human, Biotin, REAfinity™. Clone REA1085 recognizes the human CD30 antigen, a cell membrane protein, which is a member of the tumor necrosis factor receptor (TNFR) superfamily, and also known as Ki-1. CD30 is used as a tumor marker and is found on Hodgkin/Reed-Sternberg (H/RS) cells, embryonal carcinoma cells, and on activated T and B lymphocytes. It functions as a receptor for TNFSF8/CD30L and is involved in the regulation of cellular growth and transformation of activated lymphoblasts and regulates signal transduction by activation of NF-κB. | Additional information: Clone REA1085 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TNFRSF8, Ki-1, Ber-H2 |
Gene, Accession # | Gene ID: 943 |
Catalog # | 130-118-445 |
Price | $93 |
Order / More Info | CD30, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Lee, S. Y. et al. (1996) T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors. J. Exp. Med. 183 (2): 669-674. | Aizawa, S. et al. (1997) Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation. J. Biol. Chem. 272 (4): 2042-2045. | Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794. |