CD353 (SLAMF8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD353 (SLAMF8), Human |
| Clone | REA394 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD353 (SLAMF8) Antibody, anti-human, APC, REAfinity™. Clone REA394 recognizes the human CD353 antigen, a single-pass type I membrane protein, which is also known as SLAM family member 8 (SLAMF8) or B-lymphocyte activator macrophage (BLAME). CD353 is an immunoglobulin superfamily protein that is a member of the SLAM/CD150/CD2 family of receptors. It is expressed in lymphoid tissue and, more specifically, in some populations of professional APCs, activated monocytes, DCs, and upon activation of macrophages by interferon gamma (IFN-γ) or bacteria. CD353 may play a role in B lineage commitment and/or modulation of signal through the B cell receptor. | Additional information: Clone REA394 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | SLAMF8, BLAME, SBBI42 |
| Gene, Accession # | Gene ID: 56833 |
| Catalog # | 130-106-676 |
| Price | $325 |
| Order / More Info | CD353 (SLAMF8), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kingsbury, G. A. et al. (2001) Cloning, expression, and function of BLAME, a novel member of the CD2 Family. J Immunol 166 (9): 5675-5680. | Wang, G. et al. (2012) Cutting edge: Slamf8 is a negative regulator of Nox2 activity in macrophages. J Immunol 188 (12): 5829-5832. | Matesanz-Isabel, J. et al. (2011) New B-cell CD molecules. Immunol. Lett. 134 (2): 104-112. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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