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Antigenic Specificity | CD105, Human |
Clone | REA794 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 615 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD105 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA794 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin. | Additional information: Clone REA794 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ENG, END, HHT1, ORW1, Endoglin |
Gene, Accession # | Gene ID: 2022 |
Catalog # | 130-112-322 |
Price | $162 |
Order / More Info | CD105, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bellon, T. et al. (1993) Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. Eur. J. Immunol. 23 (9): 2340-2345. | Barry, F. P. et al. (1999) The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105). Biochem. Biophys. Res. Commun. 265: 134-139. | Majumdar, M. K. et al. (2000) Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. J. Cell. Physiol. 185: 98-106. |