CD158i (KIR2DS4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD158i (KIR2DS4), Human |
| Clone | REA860 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD158i (KIR2DS4) Antibody, anti-human, FITC, REAfinity™. Clone REA860 recognizes the human CD158i antigen, also known as KIR2DS4, a member of the killer immunoglobulin-like receptor (KIR) family expressed on natural killer (NK) cells and some T cells. CD158i (KIR2DS4) provides an activation signal for NK lytic activity upon interaction with its ligand, HLA-Cw4, in an antigen-independent manner. KIRs are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. The receptor family can be subdivided functionally according to the length of their cytoplasmic tail in inhibitory and activating KIRs. | Additional information: Clone REA860 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | KIR2DS4 |
| Gene, Accession # | Gene ID: 3809 |
| Catalog # | 130-114-771 |
| Price | $93 |
| Order / More Info | CD158i (KIR2DS4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196. | Kratz, G. et al. (2004) MHC Class I-independent recognition of NK-activating receptor KIR2DS4. J Immunol 173: 1819-1825. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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