CD150 (SLAM), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD150 (SLAM), Mouse
CloneREA299
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD150 (SLAM) Antibody, anti-mouse, APC, REAfinity™. Clone REA299 recognizes the mouse CD150 antigen, a 75-95 kD single-pass type I membrane protein also known as signaling lymphocyte activation molecule (SLAM). CD150 belongs to the immunoglobulin superfamily and acts as a self ligand. Expression of CD150 is found on B cells, dendritic cells and activated/memory T cells. It is involved in functions such as stimulation, proliferation and inhibition of apoptosis of B cells, stimulation and IFN-γ production in Th1 T-cell clones and recently it has been identified as the second receptor for measles virus. In combination with CD48 and CD244, CD150 is a useful marker for hematopoietic stem cell studies. | Additional information: Clone REA299 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesSLAMF1, CDw150, ESTM51, IPO-3, SLAM
Gene, Accession #Gene ID: 27218
Catalog #130-126-114
Price$94
Order / More InfoCD150 (SLAM), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBleharski, J. R. et al. (2001) Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. J Immunol 167 (6): 3167-3181. | Castro, A. G. et al. (1999) Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in T?1 and T?2 cells. J Immunol 163 (11): 5860-5870. | Wang, N. et al. (2004) The cell surface receptor SLAM controls T cell and macrophage functions. J Immunol 199 (9): 1255-1264.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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