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Antigenic Specificity | CD80, Mouse |
Clone | 16-10A1 |
Host Species | Hamster |
Reactive Species | mouse, other |
Isotype | IgG2κ |
Format | fluorescein (FITC) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD80 Antibody, anti-mouse, FITC. The monoclonal antibody 16-10A1 recognizes mouse CD80 also known as B7, B7-1 or Ly-53. The 55 kDa member of the Ig superfamily is expressed on activated B cells, macrophages and dendritic cells. The interaction of CD80 and CD152 (CTLA-4) or CD28 induces T cell proliferation and cytokine production. | |
Immunogen | n/a |
Other Names | B7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1 |
Gene, Accession # | Gene ID: 12519 |
Catalog # | 130-102-532 |
Price | $54 |
Order / More Info | CD80, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bluestone, J. A. et al. (1995) New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2 (6): 555-559. | Hathcock, K. S. et al. (1994) Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 180 (2): 631-640. | Harlan, D. M. et al. (1994) Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proc. Natl. Acad. Sci. U.S.A. 91: 3137-3141. | Razi-Wolf, Z. et al. (1992) Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells. Proc. Natl. Acad. Sci. U.S.A. 89: 4210 -4214. |