CD158d (KIR2DL4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD158d (KIR2DL4), Human |
| Clone | REA768 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD158d (KIR2DL4) Antibody, anti-human, APC, REAfinity™. Clone REA768 recognizes the human CD158d antigen, a transmembrane glycoprotein belonging to the killer cell immunoglobulin-like receptors (KIR) family, expressed by natural killer (NK) cells and subsets of CD8+ T cells. KIRs recognize polymorphic human HLA class I molecules and have inhibitory and activation functions. Binding of CD158d to its receptor HLA-G leads to the inhibition of the cytolytic NK cell function. | Additional information: Clone REA768 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | KIR2DL4, KIR103AS, 2DL4, p49, KIR103 |
| Gene, Accession # | Gene ID: 3805 |
| Catalog # | 130-112-466 |
| Price | $325 |
| Order / More Info | CD158d (KIR2DL4), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Selvakumar, A. et al. (1996) NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains. Tissue Antigens 48 (4 Pt 1): 285-294. | Valiante, N. M. et al. (1997) Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 7 (6): 739-751. | Goodridge, J. P. et al. (2007) Three common alleles of KIR2DL4 (CD158d) encode constitutively expressed, inducible and secreted receptors in NK cells. Eur. J. Immunol. 37 (1): 199-211. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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